108,880 research outputs found

    Multi-frequency imaging of perfectly conducting cracks via boundary measurements

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    Imaging of perfectly conducting crack(s) in a 2-D homogeneous medium using boundary data is studied. Based on the singular structure of the Multi-Static Response (MSR) matrix whose elements are normalized by an adequate test function at several frequencies, an imaging functional is introduced and analyzed. A non-iterative imaging procedure is proposed. Numerical experiments from noisy synthetic data show that acceptable images of single and multiple cracks are obtained.Comment: 4 pages, 3 figure

    Comment on "Spectroscopic Evidence for Multiple Order Parameter Components in the Heavy Fermion Superconductor CeCoIn5_5"

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    Recently, Rourke et al. reported point-contact spectroscopy results on the heavy-fermion superconductor CeCoIn5_5 [1]. They obtained conductance spectra on the c-axis surfaces of CeCoIn5_5 single crystals. Their major claims are two-fold: CeCoIn5_5 has i) d-wave pairing symmetry and ii) two coexisting order parameter components. In this Comment, we show that these claims are not warranted by the data presented. [1] Rourke et al., Phys. Rev. Lett. 94, 107005 (2005).Comment: accepted for publication in Phys. Rev. Lett., final for

    Soluble Epoxide Hydrolase Inhibition for Ocular Diseases: Vision for the Future

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    Ocular diseases cause visual impairment and blindness, imposing a devastating impact on quality of life and a substantial societal economic burden. Many such diseases lack universally effective pharmacotherapies. Therefore, understanding the mediators involved in their pathophysiology is necessary for the development of therapeutic strategies. To this end, the hydrolase activity of soluble epoxide hydrolase (sEH) has been explored in the context of several eye diseases, due to its implications in vascular diseases through metabolism of bioactive epoxygenated fatty acids. In this mini-review, we discuss the mounting evidence associating sEH with ocular diseases and its therapeutic value as a target. Substantial data link sEH with the retinal and choroidal neovascularization underlying diseases such as wet age-related macular degeneration, retinopathy of prematurity, and proliferative diabetic retinopathy, although some conflicting results pose challenges for the synthesis of a common mechanism. sEH also shows therapeutic relevance in non-proliferative diabetic retinopathy and diabetic keratopathy, and sEH inhibition has been tested in a uveitis model. Various approaches have been implemented to assess sEH function in the eye, including expression analyses, genetic manipulation, pharmacological targeting of sEH, and modulation of certain lipid metabolites that are upstream and downstream of sEH. On balance, sEH inhibition shows considerable promise for treating multiple eye diseases. The possibility of local delivery of inhibitors makes the eye an appealing target for future sEH drug development initiatives

    Separation of gas mixtures by centrifugation

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    Magnetohydrodynamic (MHD) centrifuge utilizing electric currents and magnetic fields produces a magnetic force which develops supersonic rotational velocities in gas mixtures. Device is superior to ordinary centrifuges because rotation of gas mixture is produced by MHD force rather than mechanical means

    Polymer Translocation througha Pore in a Membrane

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    We construct a new statistical physical model of polymer translocation through a pore in a membrane treated as the diffusion process across a free energy barrier. We determine the translocation time in terms of chain flexibility yielding an entropic barrier, as well as in terms of the driving mechanisms such as transmembrane chemical potential difference and Brownian ratchets. It turns out that, while the chemical potential differences induce pronounced effects on translocation due to the long-chain nature of the polymer, the ratchets suppress this effect and chain flexibility.Comment: 4 pages, 5 figures, published in Phys. Rev. Lett. 77, 783(1996

    Mean Field Theoretical Structure of He and Be Isotopes

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    The structures of He and Be even-even isotopes are investigated using an axially symmetric Hartree-Fock approach with a Skyrme-IIIls mean field potential. In these simple HF calculations, He and Be isotopes appear to be prolate in their ground states and Be isotopes have oblate shape isomeric states. It is also shown that there exists a level crossing when the nuclear shape changes from the prolate state to the oblate state. The single neutron levels of Be isotopes exhibit a neutron magic number 6 instead of 8 and show that the level inversion between 1/2- and 1/2+ levels occurs only for a largely deformed isotope. Protons are bound stronger in the isotope with more neutrons while neutron levels are somewhat insensitive to the number of neutrons and thus the nuclear size and also the neutron skin become larger as the neutron number increases. In these simple calculations with Skyrme-IIIls interaction no system with a clear indication of neutron halo was found among He and Be isotopes. Instead of it we have found 8He+2n, 2n+8He+2n, and 16Be+2n like chain structures with clusters of two correlated neutrons. It is also shown that 8He and 14Be in their ground states are below the neutron drip line in which all nucleons are bound with negative energy and that 16Be in its ground state is beyond the neutron drip line with two neutrons in positive energy levels.Comment: CM energy correction, 1 figure and more discussions adde

    Field Theoretic Approach to Long Range Reactions

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    We analyze bimolecular reactions that proceed by a long-ranged reactive interaction, using a field theoretic approach that takes into account fluctuations. We consider both the one-species, A+AA+A \to \emptyset reaction and the two-species, A+BA+B \to \emptyset reaction. We consider both mobile and immobile reactants, both in the presence and in the absence of adsorption.Comment: 9 pages. 4 figures. Uses svjour macros. To appear in Europ. Phys. J.
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